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Systematic review of statistical methods used in molecular marker studies in cancer.

Abstract:

BACKGROUND: There is wide interest in the use of molecular markers for the early detection of cancer, the prediction of disease outcome, and the selection of patients for chemotherapy. Despite significant and increasing research activity, to the authors' knowledge only a small number of molecular markers have been successfully integrated into clinical practice. In the current study, the experimental designs and statistical methods used in contemporary molecular marker studies are reviewed, pa...

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Publisher copy:
10.1002/cncr.23365

Authors


Vickers, AJ More by this author
Sargent, D More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Kattan, MW More by this author
Journal:
Cancer
Volume:
112
Issue:
8
Pages:
1862-1868
Publication date:
2008-04-05
DOI:
EISSN:
1097-0142
ISSN:
0008-543X
URN:
uuid:c13f00dc-22c6-48df-9665-36cdbff09940
Source identifiers:
365937
Local pid:
pubs:365937

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