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T2 mapping MRI technique quantifies carotid plaque lipid, and its depletion after statin initiation, following acute myocardial infarction

Abstract:

Background and aims

A recently-validated, highly-sensitive T2 mapping magnetic resonance (MRI) technique accurately quantifies carotid plaque lipid. The aims of this study were to determine: (i) the extent of carotid plaque lipid in patients with acute coronary syndromes (ACS); (ii) the effects of initiation of high-intensity statin on plaque lipid content and (iii) whether plaque lipid content is related to standard or ‘functional’ blood lipid measurements.

Methods

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Subgroup:
RDM Cardiovascular Medicine
Oxford college:
Linacre College
Role:
Author
ORCID:
0000-0002-3088-8878
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Subgroup:
RDM Cardiovascular Medicine
Role:
Author
ORCID:
0000-0002-0452-8756
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Subgroup:
RDM Cardiovascular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Subgroup:
RDM Cardiovascular Medicine
Role:
Author
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National Institute for Health Research More from this funder
British Heart Foundation More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Atherosclerosis Journal website
Volume:
279
Pages:
100-106
Publication date:
2018-09-06
Acceptance date:
2018-08-24
DOI:
EISSN:
1879-1484
ISSN:
0021-9150
Pubs id:
pubs:920941
URN:
uri:c1345135-e020-4d6e-ab05-41f54724f7d9
UUID:
uuid:c1345135-e020-4d6e-ab05-41f54724f7d9
Local pid:
pubs:920941

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