Journal article icon

Journal article

A common mitochondrial DNA variant is associated with idiopathic dilated cardiomyopathy in two different populations

Abstract:

Dilated Cardiomyopathy (DCM) is a devastating disease. It is a recognised manifestation of mitochondrial disease and in some cases the only clinical abnormality. Although specific mitochondrial DNA(mtDNA) mutations in tRNAleu/lle have been identified in mitochondrial disease associated with DCM, it is not known whether any mtDNA variants predispose to sporadic DCM. We aimed to determine the prevalence of a mtDNA variant (T16189C), in DCM; this variant has been previously implicated in suscept...

Expand abstract

Actions


Authors


Khogali, SS More by this author
Mayosi, BM More by this author
Beattie, JM More by this author
McKenna, W More by this author
Watkins, H More by this author
Expand authors...
Journal:
Heart
Volume:
83
Issue:
SUPPL. 1
Publication date:
2000-05-05
ISSN:
1355-6037
URN:
uuid:c11043da-eaf6-415f-b50b-8be8e9f76cee
Source identifiers:
104378
Local pid:
pubs:104378
Language:
English

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP