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Journal article

Defective regulation of the cytosolic Ca2+ activity in parathyroid cells from patients with hyperparathyroidism.

Abstract:

The parathyroid hormone (PTH) release and cytosolic Ca2+ activity were determined in normal bovine parathyroid cells and parathyroid cells obtained from patients with hyperparathyroidism (HPT). There was a sigmoid relation between the cytosolic Ca2+ activity and the extracellular calcium concentration between 0.5 and 6.0 mmol/l. The PTH release was inhibited in parallel with the rise in the cytosolic Ca2+ activity. Both the hormone release and the cytosolic Ca2+ activity were lower in cells f...

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Publication status:
Published

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Publisher copy:
10.1007/bf01116888

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Publisher:
Kluwer Academic Publishers
Journal:
Bioscience reports
Volume:
4
Issue:
11
Pages:
909-915
Publication date:
1984-11-05
DOI:
EISSN:
1573-4935
ISSN:
0144-8463
URN:
uuid:c0f3e4e7-a34a-48ae-88c0-f2309286df36
Source identifiers:
4038
Local pid:
pubs:4038

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