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Journal article

A strategy to reveal potential glycan markers from serum glycoproteins associated with breast cancer progression.

Abstract:

Aberrant glycosylation on glycoproteins that are either presented on the surface or secreted by cancer cells is a potential source of disease biomarkers and provides insights into disease pathogenesis. N-Glycans of the total serum glycoproteins from advanced breast cancer patients and healthy individuals were sequenced by HPLC with fluorescence detection coupled with exoglycosidase digestions and mass spectrometry. We observed a significant increase in a trisialylated triantennary glycan cont...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/glycob/cwn095

Authors


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Oxford Glycobiology Institute More from this funder
European Union More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
Glycobiology Journal website
Volume:
18
Issue:
12
Pages:
1105-1118
Publication date:
2008-12-05
DOI:
EISSN:
1460-2423
ISSN:
0959-6658
URN:
uuid:c0f282a5-83af-4a37-8a1c-04a63319a880
Source identifiers:
100148
Local pid:
pubs:100148

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