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Understanding vaccine induced protective immunity to Mycobacterium tuberculosis

Abstract:

The current worldwide epidemic of Mycobacterium tuberculosis infection is a huge global health problem. Widespread BCG vaccination remains a useful tool in combating this epidemic; however, its variable efficacy requires urgent development of novel vaccines against Mycobacterium tuberculosis. Such a candidate vaccine is a serotype 5 adenovirus expressing antigen 85A from M. tuberculosis (Ad85A). In animal models Ad85A confers significant protection when administered...

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Institution:
University of Oxford
Oxford college:
Linacre College
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Role:
Supervisor
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Funding agency for:
Edward Ronan
Publication date:
2011
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:c0d7b20f-e144-42f8-aa52-301d0938b0b3
Local pid:
ora:12163

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