North-south gradients in Britain for stroke and CHD: are they explained by the same factors?
BACKGROUND AND PURPOSE: The geographic variation in CHD and stroke within Great Britain is well known. We aimed to quantify these variations and to determine the contribution of established risk factors. METHODS: This prospective study consisted of 7735 men 40 to 59 years of age in 24 British towns who were followed up for 20 years from screening in 1978 to 1980. We compared age-adjusted incidences of major stroke and CHD events in southern England and the rest of Britain before and after adj...Expand abstract
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