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Journal article

Pathogen-based precision medicine for drug-resistant tuberculosis

Abstract:

The implementation of next generation sequencing techniques, such as whole genome sequencing (WGS), in tuberculosis (TB) research has enabled timely, cost-effective, and comprehensive insights into the genetic repertoire of the human pathogens of the Mycobacterium tuberculosis complex (MTBC). WGS data allow for detailed epidemiological analysis based on genomic distance of the MTBC strains under investigation, e.g. for tracing outbreaks; it can accelerate diagnostics by predicting drug resist...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.ppat.1007297

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
NDM Experimental Medicine
Role:
Author
ORCID:
0000-0003-0421-9264
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Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Pathogens Journal website
Volume:
14
Issue:
10
Pages:
e1007297
Publication date:
2018-10-18
Acceptance date:
2018-08-27
DOI:
EISSN:
1553-7374
ISSN:
1553-7366
Pubs id:
pubs:910677
URN:
uri:c0b40082-aa4f-418b-a760-09550eeadec6
UUID:
uuid:c0b40082-aa4f-418b-a760-09550eeadec6
Local pid:
pubs:910677

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