Journal article
IL-17A/F-signaling does not contribute to the initial phase of mucosal inflammation triggered by S. Typhimurium
- Abstract:
-
Salmonella enterica subspecies 1 serovar Typhimurium (S. Typhimurium) causes diarrhea and acute inflammation of the intestinal mucosa. The pro-inflammatory cytokines IL-17A and IL-17F are strongly induced in the infected mucosa but their contribution in driving the tissue inflammation is not understood. We have used the streptomycin mouse model to analyze the role of IL-17A and IL-17F and their cognate receptor IL-17RA in S. Typhimurium enterocolitis. Neutralization of IL-17A and IL-17F did n...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Version of record, pdf, 3.5MB, Terms of use)
-
- Publisher copy:
- 10.1371/journal.pone.0013804
Authors
Bibliographic Details
- Publisher:
- Public Library of Science
- Journal:
- PLoS ONE More from this journal
- Volume:
- 5
- Issue:
- 11
- Pages:
- e13804
- Publication date:
- 2010-11-23
- Acceptance date:
- 2010-10-14
- DOI:
- EISSN:
-
1932-6203
Item Description
- Language:
-
English
- Keywords:
-
- UUID:
-
uuid:c0a5598c-c3b8-407d-9b9c-ef125bfe0c06
- Local pid:
-
pubs:422318
- Source identifiers:
-
422318
- Deposit date:
-
2014-06-18
Terms of use
- Copyright holder:
- Songhet et al
- Copyright date:
- 2010
- Notes:
- © 2010 Songhet et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record