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Carbapenems versus other beta-lactams in treating severe infections in intensive care: a systematic review of randomised controlled trials.

Abstract:

Carbapenems have not been comprehensively compared in clinical trials with fourth-generation cephalosporins (4GC) and antipseudomonal penicillins (APP) in the treatment of severe infections (SI) and febrile neutropenia (FN). A systematic review of CENTRAL, EMBASE, MEDLINE and JICST-EPlus for randomised controlled trials was conducted to establish the currently available evidence. Database searching was supplemented by hand searching and contacting conference organisers. Searching was complete...

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Publication status:
Published

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Publisher copy:
10.1007/s10096-008-0472-z

Authors


Edwards, SJ More by this author
Clarke, MJ More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Population Health
Journal:
European journal of clinical microbiology and infectious diseases : official publication of the European Society of Clinical Microbiology
Volume:
27
Issue:
7
Pages:
531-543
Publication date:
2008-07-05
DOI:
EISSN:
1435-4373
ISSN:
0934-9723
URN:
uuid:c09e8cfb-a465-4f96-9641-1e5ad0608acf
Source identifiers:
79552
Local pid:
pubs:79552

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