- Abstract:
-
OBJECTIVE: Anti-tumor necrosis factor (anti-TNF) therapies are highly effective in rheumatoid arthritis (RA) and psoriatic arthritis (PsA), but a significant number of patients exhibit only a partial or no therapeutic response. Inflammation alters local and systemic metabolism, and TNF plays a role in this. We undertook this study to determine if the patient's metabolic fingerprint prior to therapy could predict responses to anti-TNF agents. METHODS: Urine was collected from 16 RA patients an...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/art.37921
-
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- Journal:
- Arthritis and rheumatism
- Volume:
- 65
- Issue:
- 6
- Pages:
- 1448-1456
- Publication date:
- 2013-06-05
- DOI:
- EISSN:
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1529-0131
- ISSN:
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0004-3591
- URN:
-
uuid:c0956053-2391-4227-88ac-5bdc1deb7c65
- Source identifiers:
-
387851
- Local pid:
- pubs:387851
- Copyright date:
- 2013
Journal article
Metabolic profiling predicts response to anti-tumor necrosis factor α therapy in patients with rheumatoid arthritis.
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