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Journal article

Structures of respiratory syncytial virus nucleocapsid protein from two crystal forms: details of potential packing interactions in the native helical form.

Abstract:

Respiratory syncytial virus (RSV) is a frequent cause of respiratory illness in infants, but there is currently no vaccine nor effective drug treatment against this virus. The RSV RNA genome is encapsidated and protected by a nucleocapsid protein; this RNA-nucleocapsid complex serves as a template for viral replication. Interest in the nucleocapsid protein has increased owing to its recent identification as the target site for novel anti-RSV compounds. The crystal structure of human respirato...

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Publication status:
Published

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Publisher copy:
10.1107/s1744309111029228

Authors


Journal:
Acta crystallographica. Section F, Structural biology and crystallization communications
Volume:
67
Issue:
Pt 10
Pages:
1179-1183
Publication date:
2011-10-01
DOI:
EISSN:
1744-3091
ISSN:
1744-3091
Source identifiers:
245822
Language:
English
Keywords:
Pubs id:
pubs:245822
UUID:
uuid:c08c488b-b6c5-4057-a597-73f1a86c0f6f
Local pid:
pubs:245822
Deposit date:
2013-11-17

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