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Journal article

Hypoxia and oxidative stress in breast cancer. Hypoxia signalling pathways.

Abstract:

Hypoxia-inducible factor-1 (HIF), which is centrally involved in physiological oxygen homeostasis, is also activated in the majority of tumours. Activation of HIF can occur through genetic mechanisms or as a result of hypoxia within the tumour microenvironment. In some cases HIF activation appears to be intimately linked to the proliferative stimulus itself. HIF affects patterns of gene expression and tumour growth, although precise effects vary between tumour types. Modulation of HIF activit...

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Publication status:
Published

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Publisher copy:
10.1186/bcr313

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
CCMP
Role:
Author
Journal:
Breast cancer research : BCR
Volume:
3
Issue:
5
Pages:
313-317
Publication date:
2001-01-01
DOI:
EISSN:
1465-542X
ISSN:
1465-5411
Source identifiers:
31962
Language:
English
Keywords:
Pubs id:
pubs:31962
UUID:
uuid:c083fe15-3c86-4db6-abb1-f6b793ddc809
Local pid:
pubs:31962
Deposit date:
2012-12-19

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