Journal article
Hypoxia and oxidative stress in breast cancer. Hypoxia signalling pathways.
- Abstract:
-
Hypoxia-inducible factor-1 (HIF), which is centrally involved in physiological oxygen homeostasis, is also activated in the majority of tumours. Activation of HIF can occur through genetic mechanisms or as a result of hypoxia within the tumour microenvironment. In some cases HIF activation appears to be intimately linked to the proliferative stimulus itself. HIF affects patterns of gene expression and tumour growth, although precise effects vary between tumour types. Modulation of HIF activit...
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- Publication status:
- Published
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- Publisher copy:
- 10.1186/bcr313
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Authors
Bibliographic Details
- Journal:
- Breast cancer research : BCR
- Volume:
- 3
- Issue:
- 5
- Pages:
- 313-317
- Publication date:
- 2001-01-01
- DOI:
- EISSN:
-
1465-542X
- ISSN:
-
1465-5411
- Source identifiers:
-
31962
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:31962
- UUID:
-
uuid:c083fe15-3c86-4db6-abb1-f6b793ddc809
- Local pid:
- pubs:31962
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2001
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