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A genetic case-control study confirms the implication of SMAD7 and TNF locus in the development of proliferative vitreoretinopathy.

Abstract:

PURPOSE: Proliferative vitreoretinopathy (PVR) is still the major cause of failure of retinal detachment (RD) surgery and although the risk for developing this complication is associated with some clinical characteristics, the correlation is far from absolute, raising the possibility of genetic susceptibility. The objective of this study was to analyze the genetic contribution to PVR in patients undergoing RD surgery, the Retina 4 Project. METHODS: A candidate gene association study was cond...

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Publisher copy:
10.1167/iovs.12-10931

Authors


Fernandez, I More by this author
Pastor, JC More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, Biomedical Research Centre
Ramkissoon, Y More by this author
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Journal:
Investigative ophthalmology and visual science
Volume:
54
Issue:
3
Pages:
1665-1678
Publication date:
2013-03-05
DOI:
EISSN:
1552-5783
ISSN:
0146-0404
URN:
uuid:c072ea1a-dd91-4fac-85ff-2056df6e8b1e
Source identifiers:
369878
Local pid:
pubs:369878

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