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The AIP (aryl hydrocarbon receptor-interacting protein) gene and its relation to the pathogenesis of pituitary adenomas.

Abstract:

Pituitary adenomas are monoclonal neoplasms that may secrete excessive quantities of their endogenous hormones, or may not be associated with any obvious syndrome, in which case they are known as non-functioning pituitary adenomas. Around 2 % have been said to occur in a familial setting, in the absence of any other tumor, now described as familial isolated pituitary adenomas (FIPA). Some 15-30 % of such families harbor inactivating germ-line mutations in the aryl hydrocarbon receptor-interac...

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Publication status:
Published

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Publisher copy:
10.1007/s12020-013-0125-6

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Journal:
Endocrine
Volume:
46
Issue:
3
Pages:
387-396
Publication date:
2014-08-05
DOI:
EISSN:
1559-0100
ISSN:
1355-008X
URN:
uuid:c05559b0-93c7-4037-a40f-fb948097499c
Source identifiers:
444283
Local pid:
pubs:444283
Language:
English
Keywords:

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