Thesis

### Tumour-stromal interactions in cancer progression and drug resistance

Abstract:

The typical response of cancer patients to treatment is only temporary, and is often followed by relapse. The failure of various therapeutic strategies is commonly attributed to the emergence of drug resistance. The response patterns for patients under such treatments indicate that complex dynamics regulate the response of the tumour to the therapy. The environment in which the tumour lives (the stroma) is known to be a modulator of multiple mechanisms that lead to drug resistance and seem...

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### Authors

#### Contributors

Department:
Mathematical Institute
Role:
Supervisor
Department:
H Lee Moffitt Cancer Center
Role:
Supervisor
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Grant:
U01CA151924
Funding agency for:
Project
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Grant:
EP/G037280/1
Funding agency for:
Noemi Picco
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects: