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Journal article

Impact of age and retinal degeneration on the light input to circadian brain structures.

Abstract:

Aging causes anatomical and functional changes in visual and circadian systems. In wild type mice rods, cones, and photosensitive retinal ganglion cells (pRGCs) decline with age. In rd/rd cl mice, the early loss of rods and cones is followed by protracted transneuronal loss of inner retinal neurons as well as the pRGCs. Here we use Fos induction to study the light input pathway to the suprachiasmatic nuclei (SCN), the intergeniculate leaflets (IGL) and ventral lateral geniculate nuclei (vLGN)...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neurosciences
Role:
Author
Journal:
Neurobiology of aging
Volume:
33
Issue:
2
Pages:
383-392
Publication date:
2012-02-05
DOI:
EISSN:
1558-1497
ISSN:
0197-4580
URN:
uuid:c03032c2-69be-49a9-8e27-db36c3c193a8
Source identifiers:
101503
Local pid:
pubs:101503

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