Genome-wide association studies (GWASs) have been successful at identifying single-nucleotide polymorphisms (SNPs) highly associated with common traits; however, a great deal of the heritable variation associated with common traits remains unaccounted for within the genome. Genome-wide complex trait analysis (GCTA) is a statistical method that applies a linear mixed model to estimate phenotypic variance of complex traits explained by genome-wide SNPs, including those not associated with the t...Expand abstract
- Publisher copy:
- Copyright date:
Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease.
If you are the owner of this record, you can report an update to it here: Report update to this record