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The aurora B kinase promotes inner and outer kinetochore interactions in budding yeast.

Abstract:
The kinetochore is the macromolecular protein complex that mediates chromosome segregation. The Dsn1 component is crucial for kinetochore assembly and is phosphorylated by the Aurora B kinase. We found that Aurora B phosphorylation of Dsn1 promotes the interaction between outer and inner kinetochore proteins in budding yeast.

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Publisher copy:
10.1534/genetics.113.150839

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Nelson, CR More by this author
Biggins, S More by this author
Journal:
Genetics
Volume:
194
Issue:
3
Pages:
785-789
Publication date:
2013-07-05
DOI:
EISSN:
1943-2631
ISSN:
0016-6731
URN:
uuid:c0114c9b-45f9-4d34-bebe-26946dbdb6e4
Source identifiers:
402080
Local pid:
pubs:402080

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