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Nanoengineering of Immune Cell Function.

Abstract:

T lymphocytes are a key regulatory component of the adaptive immune system. Understanding how the micro- and nano-scale details of the extracellular environment influence T cell activation may have wide impact on the use of T cells for therapeutic purposes. In this article, we examine how the micro- and nano-scale presentation of ligands to cell surface receptors, including microscale organization and nanoscale mobility, influences the activation of T cells. We extend these studies to include...

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Publisher copy:
10.1557/proc-1209-yy03-01

Authors


Milone, MC More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Journal:
Materials Research Society symposia proceedings. Materials Research Society
Volume:
1209
Pages:
141-150
Publication date:
2009-01-05
DOI:
EISSN:
1946-4274
ISSN:
0272-9172
URN:
uuid:bff511a1-e394-4e4c-b9e0-ac39d487a0ed
Source identifiers:
426304
Local pid:
pubs:426304
Language:
English

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