Ly-6C is a marker of memory CD8+ T cells.
This study examined long-term phenotypic and functional effects of TCR ligation in vivo. Flow cytometric analysis of T cells from mice treated with anti-CD3 revealed an increase in CD44 expression in both the CD4+ and CD8+ populations. The phenotypic changes were a result of TCR engagement, because treatment with staphylococcal enterotoxin B (SEB) resulted in a preferential increase in CD44 expression on the SEB-reactive V beta 8 T cells. In addition, the percentage of cells expressing Ly-6C ...Expand abstract
- Journal of immunology (Baltimore, Md. : 1950)
- Publication date:
- Source identifiers:
- Local pid:
- Copyright date: