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Journal article

Ly-6C is a marker of memory CD8+ T cells.

Abstract:

This study examined long-term phenotypic and functional effects of TCR ligation in vivo. Flow cytometric analysis of T cells from mice treated with anti-CD3 revealed an increase in CD44 expression in both the CD4+ and CD8+ populations. The phenotypic changes were a result of TCR engagement, because treatment with staphylococcal enterotoxin B (SEB) resulted in a preferential increase in CD44 expression on the SEB-reactive V beta 8 T cells. In addition, the percentage of cells expressing Ly-6C ...

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Journal:
Journal of Immunology
Volume:
155
Issue:
4
Pages:
1873-1883
Publication date:
1995-08-01
EISSN:
1550-6606
ISSN:
0022-1767
Source identifiers:
483519

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