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Neutrophil extracellular traps, local IL-8 expression, and cytotoxic T-lymphocyte response in the lungs of patients with fatal COVID-19

Abstract:
Background
Excessive inflammation is pathogenic in the pneumonitis associated with severe COVID-19. Neutrophils are among the most abundantly present leukocytes in the inflammatory infiltrates and may form neutrophil extracellular traps (NETs) under the local influence of cytokines. NETs constitute a defense mechanism against bacteria, but have also been shown to mediate tissue damage in a number of diseases.
Research Question
Could NETs and their... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1016/j.chest.2022.06.007

Authors


Publisher:
Elsevier
Journal:
Chest Journal More from this journal
Volume:
162
Issue:
5
Pages:
1006-1016
Publication date:
2022-06-14
Acceptance date:
2022-06-07
DOI:
EISSN:
1931-3543
ISSN:
0012-3692
Pmid:
35714708
Language:
English
Keywords:
Pubs id:
1265742
Local pid:
pubs:1265742
Deposit date:
2022-09-02

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