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Thesis

The influence of selected sulphur containing compounds on retinal cell death: neuroprotective effects of hydrogen sulphide in a glaucoma model

Abstract:

Ganglion cell death in glaucoma is caused by a variety of insults that include ischemia, insufficient neurotrophic support and oxidative stress. Experimental studies were therefore conducted on cell cultures to determine how serum deprivation (to mimic insufficient neurotrophic support) or oxidative glutamate toxicity (GB), cause oxidative stress and induce retinal cell death. Moreover, studies were carried out to deduce whether selected sulphur containing compounds can blunt any negative ...

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Institution:
University of Oxford
Oxford college:
Green College
Department:
Medical Sciences Division - Ophthalmology
Role:
Author

Contributors

Role:
Supervisor
Publication date:
2011
Type of award:
DPhil
Level of award:
Doctoral
URN:
uuid:bfb5ec82-9141-4784-94a8-0df3ce9d9471
Local pid:
ora:12088

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