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Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease.

Abstract:

BACKGROUND: Previous Cochrane reviews have considered the use of cholinesterase inhibitors in both Parkinson's disease with dementia (PDD) and dementia with Lewy bodies (DLB). The clinical features of DLB and PDD have much in common and are distinguished primarily on the basis of whether or not parkinsonism precedes dementia by more than a year. Patients with both conditions have particularly severe deficits in cortical levels of the neurotransmitter acetylcholine. Therefore, blocking its br...

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Publication status:
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Maidment, I More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Stroke and Geratology
Journal:
The Cochrane database of systematic reviews
Volume:
3
Issue:
3
Pages:
CD006504
Publication date:
2012
DOI:
EISSN:
1469-493X
ISSN:
1469-493X
URN:
uuid:bfb44746-010b-479a-bb87-36bfc6b4d1c9
Source identifiers:
316234
Local pid:
pubs:316234

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