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Genome sequencing reveals a large and diverse repertoire of antimicrobial peptides

Abstract:

Competition among bacterial members of the same ecological niche is mediated by bacteriocins: antimicrobial peptides produced by bacterial species to kill other bacteria. Bacteriocins are also promising candidates for novel antimicrobials. Streptococcus pneumoniae (the ‘pneumococcus’) is a leading cause of morbidity and mortality worldwide and a frequent coloniser of the human nasopharynx. Here, 14 newly-discovered bacteriocin gene clusters were identified among >6,200 pneumococcal genomes...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.3389/fmicb.2018.02012

Authors


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Institution:
University of Oxford
Division:
Medical Sciences
Department:
Experimental Medicine
Van Tonder, AJ More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences
Department:
Doctoral Training Centre
More by this author
Institution:
University of Oxford
Division:
Medical Sciences
Department:
Experimental Medicine
Oxford college:
St Catherine's College
ORCID:
0000-0002-2329-1934
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Funding agency for:
Brueggemann, AB
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Funding agency for:
Brueggemann, AB
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Funding agency for:
Brueggemann, AB
Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Microbiology Journal website
Volume:
9
Publication date:
2018-08-27
Acceptance date:
2018-08-09
DOI:
EISSN:
1664-302X
Pubs id:
pubs:905695
URN:
uri:bf9db92b-4720-4998-ba36-bbb058e1f36d
UUID:
uuid:bf9db92b-4720-4998-ba36-bbb058e1f36d
Local pid:
pubs:905695

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