- Abstract:
-
The structure of the complex between d(TGATCA) and the anthracycline 4'-epiadriamycin has been determined by crystallographic methods. The crystals are tetragonal, space group P4(1)2(1)2 with unit cell dimensions of a = 28.01, c = 52.95A. The asymmetric unit consists of one strand of hexanucleotide, one molecule of 4'-epiadriamycin and 34 waters. The R-factor is 20.2% for 1694 reflections with F greater than or equal to 2 sigma F to 1.7A. Two asymmetric units associate to generate a duplex co...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1093/nar/20.14.3561
-
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- Journal:
- Nucleic acids research
- Volume:
- 20
- Issue:
- 14
- Pages:
- 3561-3566
- Publication date:
- 1992-07-05
- DOI:
- EISSN:
-
1362-4962
- ISSN:
-
0305-1048
- URN:
-
uuid:bf8d649b-d01b-45a5-8a72-2fde054d1a70
- Source identifiers:
-
400400
- Local pid:
- pubs:400400
- Language:
- English
- Keywords:
- Copyright date:
- 1992
Journal article
The molecular structure of a 4'-epiadriamycin complex with d(TGATCA) at 1.7A resolution: comparison with the structure of 4'-epiadriamycin d(TGTACA) and d(CGATCG) complexes.
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