Journal article icon

Journal article

Genetics of multiple sclerosis.

Abstract:

Multiple Sclerosis (MS) is a common chronic central nervous system disease in young adults. Relative familial risk appears to be determined largely by genes while population risk is strongly influenced by environmental factors. This is supported by genetic epidemiological studies which also suggest an oligogenic inheritance of susceptibility. The HLA DRB1*1501, DQA1*0102, DQB1 0602 haplotype is associated with the disease but HLA contributes only modestly to overall susceptibility. The result...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1093/hmg/6.10.1693

Authors


Dyment, DA More by this author
Sadovnick, AD More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, WTC Human Genetics
Sadnovich, AD More by this author
Journal:
Human molecular genetics
Volume:
6
Issue:
10
Pages:
1693-1698
Publication date:
1997
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:bf614799-dff2-49fa-9e6b-7af04817c0b5
Source identifiers:
36094
Local pid:
pubs:36094

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP