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Journal article

Genetics of multiple sclerosis.

Abstract:

Multiple Sclerosis (MS) is a common chronic central nervous system disease in young adults. Relative familial risk appears to be determined largely by genes while population risk is strongly influenced by environmental factors. This is supported by genetic epidemiological studies which also suggest an oligogenic inheritance of susceptibility. The HLA DRB1*1501, DQA1*0102, DQB1 0602 haplotype is associated with the disease but HLA contributes only modestly to overall susceptibility. The result...

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Publication status:
Published

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Publisher copy:
10.1093/hmg/6.10.1693

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, WTC Human Genetics
Role:
Author
Journal:
Human molecular genetics
Volume:
6
Issue:
10
Pages:
1693-1698
Publication date:
1997-01-01
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:bf614799-dff2-49fa-9e6b-7af04817c0b5
Source identifiers:
36094
Local pid:
pubs:36094

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