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Journal article

Effect of membrane potential on surface Ca2+ receptor activation in rat osteoclasts.

Abstract:

Osteoclasts are known to possess a divalent cation-sensitive receptor, the Ca2+ receptor (CaR). The latter monitors changes in the local Ca2+ concentration generated as a result of hydroxyapatite dissolution. CaR activation elevates cytosolic [Ca2+] and thereby inhibits osteoclastic bone resorption. Recent studies have used Ni2+ as a surrogate CaR agonist to elicit changes in cytosolic [Ca2+]. This article examines the effects of membrane potential changes on the kinetics of the cytosolic [Ca...

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Publisher copy:
10.1002/jcp.1041620102

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Journal:
Journal of cellular physiology
Volume:
162
Issue:
1
Pages:
1-8
Publication date:
1995-01-05
DOI:
EISSN:
1097-4652
ISSN:
0021-9541
URN:
uuid:bf37f115-71df-43f1-9b03-e3eda23ee1be
Source identifiers:
475701
Local pid:
pubs:475701

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