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Ccoffinn: Automated wave tracking in cultured cardiac monolayers.

Abstract:

Cardiac arrhythmias are one of the most frequent causes of death worldwide. A popular biological model used to study arrhythmogenesis is the cultured cardiac cell monolayer, which provides a good trade-off between physiological relevance and experimental access. Excitation wave patterns are imaged using high-bandwidth detectors, producing large data sets that are typically analyzed manually. To make such analysis less time consuming and less subjective, we have designed and implemented a tool...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.bpj.2016.08.049

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Department:
Oxford, MSD, Physiology Anatomy and Genetics
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Department:
Oxford, MSD, Pharmacology
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Funding agency for:
Tomek, J
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Funding agency for:
Burton, R-A
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Publisher:
Elsevier Publisher's website
Journal:
Biophysical Journal Journal website
Volume:
111
Issue:
8
Pages:
1595-1599
Publication date:
2016-10-05
Acceptance date:
2016-08-26
DOI:
ISSN:
1542-0086 and 0006-3495
Pubs id:
pubs:653684
URN:
uri:bf1b6915-7b77-47a3-99e1-39a8c082b916
UUID:
uuid:bf1b6915-7b77-47a3-99e1-39a8c082b916
Local pid:
pubs:653684
Language:
English
Keywords:

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