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Journal article

Myocardial perfusion and oxygenation are impaired during stress in severe aortic stenosis and correlate with impaired energetics and subclinical left ventricular dysfunction.

Abstract:

BACKGROUND: Left ventricular (LV) hypertrophy in aortic stenosis (AS) is characterized by reduced myocardial perfusion reserve due to coronary microvascular dysfunction. However, whether this hypoperfusion leads to tissue deoxygenation is unknown. We aimed to assess myocardial oxygenation in severe AS without obstructive coronary artery disease, and to investigate its association with myocardial energetics and function. METHODS: Twenty-eight patients with isolated severe AS and 15 controls un...

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Publication status:
Published

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Publisher copy:
10.1186/1532-429x-16-29

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Journal:
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
Volume:
16
Pages:
29
Publication date:
2014-01-01
DOI:
EISSN:
1532-429X
ISSN:
1097-6647
URN:
uuid:bebc2c7b-ca79-4766-b458-1b391bea5f11
Source identifiers:
464908
Local pid:
pubs:464908

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