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Journal article

The BTB-ZF transcription factors.

Abstract:
The BTB-ZF (broad-complex, tramtrack and bric-à-brac--zinc finger) proteins are encoded by at least 49 genes in mouse and man and commonly serve as sequence-specific silencers of gene expression. This review will focus on the known physiological functions of mammalian BTB-ZF proteins, which include essential roles in the development of the immune system. We discuss their function in terminally differentiated lymphocytes and the progenitors that give rise to them, their action in hematopoietic malignancy and roles beyond the immune system.
Publication status:
Published

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Publisher copy:
10.4161/cc.21277

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Beutler, B More by this author
Journal:
Cell cycle (Georgetown, Tex.)
Volume:
11
Issue:
18
Pages:
3358-3369
Publication date:
2012-09-05
DOI:
EISSN:
1551-4005
ISSN:
1538-4101
URN:
uuid:be9fe54e-7559-4a09-b945-a5f04eb248cb
Source identifiers:
418813
Local pid:
pubs:418813

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