Teleost fish spermatozoa contain a cytosolic protein factor that induces calcium release in sea urchin egg homogenates and triggers calcium oscillations when injected into mouse oocytes.

Journal article

Established studies in a variety of organisms including amphibians, fish, ascidians, nemerteans, echinoderms, mammals, and even a species of flowering plant, clearly demonstrate that an increase in intracellular egg calcium is crucial to the process of egg activation at fertilization. In echinoderms, egg activation appears to involve an egg phospholipase C gamma (PLCgamma). However, numerous studies in mammalian species suggest that calcium is released from internal egg stores at fertilizatio...

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Authors: Coward, K; Campos-Mendoza, A; Larman, M; Hibbitt, O; McAndrew, B

• Publication status: Published
• Journal: Biochemical and biophysical research communications
• Volume: 305
• Issue: 2
• Pages: 299-304
• Publication date: 2003-05-01
• DOI: 10.1016/s0006-291x(03)00753-8
• EISSN: 1090-2104
• ISSN: 0006-291X
• Language: English
• Keywords: Spermatozoa; Injections; Cell Extracts; Tilapia; Biological Assay; Cytosol; Type C Phospholipases; Oocytes; Mice; Male; Proteins; Ovum; Calcium Signaling; Calcium; Kinetics; Animals; Sea Urchins