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Genomic acquisition of a capsular polysaccharide virulence cluster by non-pathogenic Burkholderia isolates.

Abstract:

BACKGROUND: Burkholderia thailandensis is a non-pathogenic environmental saprophyte closely related to Burkholderia pseudomallei, the causative agent of the often fatal animal and human disease melioidosis. To study B. thailandensis genomic variation, we profiled 50 isolates using a pan-genome microarray comprising genomic elements from 28 Burkholderia strains and species. RESULTS: Of 39 genomic regions variably present across the B. thailandensis strains, 13 regions corresponded to known ge...

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Publication status:
Published

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Publisher copy:
10.1186/gb-2010-11-8-r89

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
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Journal:
Genome biology
Volume:
11
Issue:
8
Pages:
R89
Publication date:
2010-01-01
DOI:
EISSN:
1465-6914
ISSN:
1465-6906
Source identifiers:
133482
Language:
English
Keywords:
Pubs id:
pubs:133482
UUID:
uuid:be6720bf-0ebd-432c-99e8-fb85680a7ace
Local pid:
pubs:133482
Deposit date:
2014-07-17

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