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Genomic acquisition of a capsular polysaccharide virulence cluster by non-pathogenic Burkholderia isolates.

Abstract:

BACKGROUND: Burkholderia thailandensis is a non-pathogenic environmental saprophyte closely related to Burkholderia pseudomallei, the causative agent of the often fatal animal and human disease melioidosis. To study B. thailandensis genomic variation, we profiled 50 isolates using a pan-genome microarray comprising genomic elements from 28 Burkholderia strains and species. RESULTS: Of 39 genomic regions variably present across the B. thailandensis strains, 13 regions corresponded to known ge...

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Publication status:
Published

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Publisher copy:
10.1186/gb-2010-11-8-r89

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
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Journal:
Genome biology
Volume:
11
Issue:
8
Pages:
R89
Publication date:
2010
DOI:
EISSN:
1465-6914
ISSN:
1465-6906
URN:
uuid:be6720bf-0ebd-432c-99e8-fb85680a7ace
Source identifiers:
133482
Local pid:
pubs:133482

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