- Abstract:
-
Modulation of Ca(2+) homoeostasis in cardiac myocytes plays a major role in beat-to-beat regulation of heart function. Previous studies suggest that sphingosine-1-phosphate (S1P), a biologically active sphingomyelin metabolite, regulates Ca(2+) handling in cardiac myocytes, but the underlying mechanism is unclear. In the present study, we tested the hypothesis that S1P-induced functional alteration of intracellular Ca(2+) handling includes the L-type calcium channel current (ICa,L) via a sign...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted manuscript
- Files:
-
-
(pdf, 148.7KB)
-
- Publisher copy:
- 10.1007/s11010-016-2752-8
-
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- Publisher:
- Springer Verlag Publisher's website
- Journal:
- Molecular and Cellular Biochemistry Journal website
- Volume:
- 419
- Issue:
- 1
- Pages:
- 83-92
- Publication date:
- 2016-07-02
- Acceptance date:
- 2016-06-21
- DOI:
- EISSN:
-
1573-4919
- ISSN:
-
0300-8177
- Pubs id:
-
pubs:634205
- URN:
-
uri:be505d10-f188-4a8b-ae79-705f03d16722
- UUID:
-
uuid:be505d10-f188-4a8b-ae79-705f03d16722
- Local pid:
- pubs:634205
- Paper number:
- 1
- Language:
- English
- Keywords:
- Copyright holder:
- Springer Science+Business Media
- Copyright date:
- 2016
- Notes:
- © Springer Science+Business Media New York 2016. This is the accepted manuscript version of the article. The final version is available online from Springer at: [10.1007/s11010-016-2752-8]
Journal article
Effect of sphingosine-1-phosphate on L-type calcium current and Ca(2+) transient in rat ventricular myocytes.
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