Five-year follow-up of patients with primary antibody deficiencies following an outbreak of acute hepatitis C.

Journal article

This report is the 5-year follow-up of those 25 UK patients with primary antibody deficiencies infected with hepatitis C virus (HCV), type 1a, from one batch of contaminated anti-HCV-screened intravenous immunoglobulin in 1993-1994. Of these patients, who were reported previously (1, 2), 2 cleared HCV spontaneously, 18 received early interferon-alpha (IFN) treatment for 6 months, and 5 declined treatment or treatment was contraindicated. The clinical course of this cohort was followed prospec...

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Authors: Chapel, H; Christie, J; Peach, V; Chapman, R

• Journal: Clinical immunology (Orlando, Fla.)
• Volume: 99
• Issue: 3
• Pages: 320-324
• Publication date: 2001-06-01
• DOI: 10.1006/clim.2001.5036
• EISSN: 1521-7035
• ISSN: 1521-6616
• Language: English
• Keywords: Middle Aged; Adult; Disease Outbreaks; RNA, Viral; Male; Hepatitis C; Great Britain; Adolescent; Aged; Child, Preschool; Interferon-alpha; Follow-Up Studies; Female; Immunologic Deficiency Syndromes; Humans; Acute Disease