Journal article
Cytokine-stimulated T cells induce macrophage IL-10 production dependent on phosphatidylinositol 3-kinase and p70S6K: implications for rheumatoid arthritis.
- Abstract:
-
IL-10 is an anti-inflammatory cytokine produced in the joint in rheumatoid arthritis by macrophages and infiltrating blood lymphocytes. Regulation of its expression is poorly understood, but previous findings have suggested that physical interactions with T cells may play a role. This report investigates signalling mechanisms involved in the production of macrophage IL-10 upon interaction with fixed, cytokine-stimulated T cells (Tck). Elutriated monocytes were differentiated to macrophages by...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Arthritis research
- Volume:
- 4
- Issue:
- 1
- Pages:
- 64-70
- Publication date:
- 2002-01-01
- DOI:
- EISSN:
-
1465-9913
- ISSN:
-
1465-9905
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:224146
- UUID:
-
uuid:be23b904-bba6-4b13-baf2-fafc0bbd2238
- Local pid:
- pubs:224146
- Source identifiers:
-
224146
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2002
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