Journal article
Epiregulin (EREG) variation is associated with susceptibility to tuberculosis
- Abstract:
-
Although host genetics influences susceptibility to Mycobacterium tuberculosis, the human genes regulating pathogenesis remain largely unknown. We used M. tuberculosis-stimulated macrophage gene expression profiling in conjunction with a case-control genetic association study to discover epiregulin (EREG), as a novel candidate tuberculosis (TB) susceptibility gene. Using a genome-wide association study dataset, we found that among the 21 genes with greater than 50-fold induction, EREG had the...
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Bibliographic Details
- Journal:
- Genes and Immunity More from this journal
- Volume:
- 13
- Issue:
- 3
- Pages:
- 275-281
- Publication date:
- 2012-04-01
- DOI:
- EISSN:
-
1476-5470
- ISSN:
-
1466-4879
Item Description
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:325407
- UUID:
-
uuid:bde4cd70-4f60-4f6b-a172-b9177a9dbb94
- Local pid:
-
pubs:325407
- Source identifiers:
-
325407
- Deposit date:
-
2012-12-19
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- Copyright date:
- 2012
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