Journal article icon

Journal article

Epiregulin (EREG) variation is associated with susceptibility to tuberculosis

Abstract:

Although host genetics influences susceptibility to Mycobacterium tuberculosis, the human genes regulating pathogenesis remain largely unknown. We used M. tuberculosis-stimulated macrophage gene expression profiling in conjunction with a case-control genetic association study to discover epiregulin (EREG), as a novel candidate tuberculosis (TB) susceptibility gene. Using a genome-wide association study dataset, we found that among the 21 genes with greater than 50-fold induction, EREG had the...

Expand abstract

Actions


Access Document


Publisher copy:
10.1038/gene.2011.83

Authors


Journal:
Genes and Immunity More from this journal
Volume:
13
Issue:
3
Pages:
275-281
Publication date:
2012-04-01
DOI:
EISSN:
1476-5470
ISSN:
1466-4879
Language:
English
Keywords:
Pubs id:
pubs:325407
UUID:
uuid:bde4cd70-4f60-4f6b-a172-b9177a9dbb94
Local pid:
pubs:325407
Source identifiers:
325407
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP