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Journal article

Coadministration of seasonal influenza vaccine and MVA-NP+M1 simultaneously achieves potent humoral and cell-mediated responses.

Abstract:

Current seasonal influenza vaccines have reduced immunogenicity and are of suboptimal efficacy in older adults. We have previously shown that the novel candidate vaccine MVA-NP+M1 is able to boost memory T cell responses in adults aged 50-85 years. Preclinical studies have demonstrated that viral vectored vaccines can act as adjuvants when coadministered with protein-based vaccines. We have conducted a phase I clinical trial to compare the coadministration of seasonal influenza vaccine and MV...

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Publication status:
Published

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Publisher copy:
10.1038/mt.2013.162

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Journal:
Molecular therapy : the journal of the American Society of Gene Therapy
Volume:
22
Issue:
1
Pages:
233-238
Publication date:
2014-01-05
DOI:
EISSN:
1525-0024
ISSN:
1525-0016
URN:
uuid:bdcfca73-8a51-4943-bce9-959e2eaf09db
Source identifiers:
410917
Local pid:
pubs:410917

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