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Gametocyte dynamics and the role of drugs in reducing the transmission potential of Plasmodium vivax.

Abstract:

BACKGROUND: Designing interventions that will reduce transmission of vivax malaria requires knowledge of Plasmodium vivax gametocyte dynamics. METHODS: We analyzed data from a randomized controlled trial in northwestern Thailand and 2 trials in Papua, Indonesia, to identify and compare risk factors for vivax gametocytemia at enrollment and following treatment. RESULTS: A total of 492 patients with P. vivax infections from Thailand and 476 patients (162 with concurrent falciparum parasitemia) ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/infdis/jit261

Authors


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Institution:
University of Oxford
Simpson, JA More by this author
Siswantoro, H More by this author
Hasugian, AR More by this author
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Funding agency for:
Douglas, NM
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Funding agency for:
White, NJ
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Funding agency for:
Price, RN
Wellcome Trust More from this funder
Holleypharm (R. P. C.) More from this funder
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Publisher:
Oxford University Press Publisher's website
Journal:
The Journal of infectious diseases Journal website
Volume:
208
Issue:
5
Pages:
801-812
Publication date:
2013-09-05
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
URN:
uuid:bdaf8196-0ece-4300-986c-db1e03ea5f4c
Source identifiers:
407800
Local pid:
pubs:407800

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