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Dopamine release and uptake dynamics within nonhuman primate striatum in vitro.

Abstract:

The putamen of the human striatum is a heterogeneous nucleus that contains the primary site of loss of dopamine (DA) in Parkinson's disease (PD). Furthermore, different functional domains of the putamen are heterogeneously susceptible to DA loss, and yet the dynamic regulation of extracellular DA concentration ([DA](o)) and comparison between domains has not been explored in the primate brain. In these studies, DA was measured in real time using fast-scan cyclic voltammetry at a carbon-fiber ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
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Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology
Journal:
The Journal of neuroscience : the official journal of the Society for Neuroscience
Volume:
20
Issue:
21
Pages:
8209-8217
Publication date:
2000-11-05
EISSN:
1529-2401
ISSN:
0270-6474
URN:
uuid:bda38468-92fa-4e1b-9316-3a6f40df101d
Source identifiers:
114047
Local pid:
pubs:114047

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