Thesis
Synthetic approaches towards phorbols
- Abstract:
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The work described herein is concerned with the synthesis of phorbol natural products. The approach to these biological derivatives explored in this study utilised an intramolecular Diels- Alder reaction of a furan diene (IMDAF) precursor to establish the tigliane hydrocarbon skeleton and an intramolecular aldol cyclisation to construct the functionalised A-ring. Additionally, the subsequent elaboration of the phorboid cycloadducts could access highly functionalised ingenane analogues by ...
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Bibliographic Details
- Publication date:
- 1994
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Source identifiers:
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603835510
Item Description
Terms of use
- Copyright holder:
- M. C. Bagley
- Copyright date:
- 1994
- Notes:
- This thesis was digitised thanks to the generosity of Dr Leonard Polonsky.
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