Imaging in Cushing's syndrome.

Journal article

Once the diagnosis of Cushing's syndrome (CS) has been established, the main step is to differentiate between ACTH dependent and independent disease. In adults, 80% of CS is due to ACTH-dependent causes and 20% due to adrenal causes. ACTH-secreting neoplasms cause ACTH-dependent CS. These are usually anterior pituitary microadenomas, which result in the classic Cushing's disease. Non-pituitary ectopic sources of ACTH, such as a small-cell lung carcinoma or carcinoid tumours, are the source of...

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Authors: Sahdev, A; Reznek, R; Evanson, J; Grossman, AB

• Publication status: Published
• Journal: Arquivos brasileiros de endocrinologia e metabologia
• Volume: 51
• Issue: 8
• Pages: 1319-1328
• Publication date: 2007-11-01
• DOI: 10.1590/s0004-27302007000800018
• EISSN: 1677-9487
• ISSN: 0004-2730
• Language: English
• Keywords: Humans; ACTH-Secreting Pituitary Adenoma; Tomography, X-Ray Computed; Adrenal Gland Neoplasms; Magnetic Resonance Imaging; Hyperplasia; Pituitary Neoplasms; Pituitary Gland; Cushing Syndrome; Adenoma; ACTH Syndrome, Ectopic; Carcinoma; Lung Neoplasms