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Host biomarkers reflect prognosis in patients presenting with moderate coronavirus disease 2019: a prospective cohort study

Abstract:
Efficient resource allocation is essential for effective pandemic response. We measured host biomarkers in 420 patients presenting with moderate coronavirus disease 2019 and found that different biomarkers predict distinct clinical outcomes. Interleukin (IL)-1ra, IL-6, IL-10, and IL-8 exhibit dose-response relationships with subsequent disease progression and could potentially be useful for multiple use-cases.
Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1093/ofid/ofac526

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0003-1313-7922
More by this author
Role:
Author
ORCID:
0000-0001-6788-2835
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author

Contributors

Publisher:
Oxford University Press
Journal:
Open Forum Infectious Diseases More from this journal
Volume:
9
Issue:
10
Article number:
ofac526
Place of publication:
United States
Publication date:
2022-10-06
Acceptance date:
2022-10-04
DOI:
EISSN:
2328-8957
Pmid:
36320192
Language:
English
Keywords:
Pubs id:
1300660
Local pid:
pubs:1300660
Deposit date:
2024-05-09

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