We have studied the effects of stimulating the pedunculopontine nuclei through a fully implanted macroelectrode with a s.c. implantable pulse generator whose parameters can be programmed telemetrically, in a macaque before and after inducing Parkinsonian akinesia with MPTP. Our results show that in the normal monkey high frequency stimulation of the pedunculopontine nuclei reduces motor activity while low frequency stimulation increases it significantly over baseline. After making the monkey ...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
Pedunculopontine nucleus stimulation improves akinesia in a Parkinsonian monkey.
Views and Downloads
If you are the owner of this record, you can report an update to it here: Report update to this record