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Thesis

Functional evaluation of the human fat distribution HOXC13 gene locus

Abstract:

Gynoid fat distinguishes from android fat in developmental origin and possesses metabolically protective roles, especially in women. Growing evidence supports that epigenetic modifications could potentially explain the regional differences between fat depots. Recent progress in transcriptome analysis has revealed that long non-coding RNAs (lncRNAs) play roles in epigenetic regulation, but their potential functions in fat depot-specific transcription remain largely unexplored. HOX transcrip...

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Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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