- Abstract:
-
The immune system must be highly regulated to obtain optimal immune responses for the elimination of pathogens without causing undue side effects. This tight regulation involves complex interactions between membrane proteins on leukocytes. Members of the signal-regulatory protein (SIRP) family, which are expressed mainly by myeloid cells, provide one example of these regulatory membrane proteins. There are three SIRP-family genes that encode proteins that have similar extracellular regions bu...
Expand abstract - Publisher copy:
- 10.1038/nri1859
-
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- Journal:
- Nature Reviews Immunology
- Volume:
- 6
- Issue:
- 6
- Pages:
- 457-464
- Publication date:
- 2006-06-05
- DOI:
- ISSN:
-
1474-1733
- URN:
-
uuid:bd33dbbf-8603-4b87-a00d-e0f1f7a485a4
- Source identifiers:
-
171842
- Local pid:
- pubs:171842
- Language:
- English
- Copyright date:
- 2006
Journal article
The SIRP family of receptors and immune regulation
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