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Site and gender specificity of inheritance of bone mineral density.

Abstract:

UNLABELLED: Differences in genetic control of BMD by skeletal sites and genders were examined by complex segregation analysis in 816 members of 147 families with probands with extreme low BMD. Spine BMD correlated more strongly in male-male comparisons and hip BMD in female-female comparisons, consistent with gender- and site-specificity of BMD heritability. INTRODUCTION: Evidence from studies in animals and humans suggests that the genetic control of bone mineral density (BMD) may differ at...

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Publication status:
Published

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Publisher copy:
10.1359/jbmr.2003.18.8.1531

Authors


Duncan, EL More by this author
Cardon, LR More by this author
Sinsheimer, JS More by this author
Journal:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Volume:
18
Issue:
8
Pages:
1531-1538
Publication date:
2003-08-05
DOI:
EISSN:
1523-4681
ISSN:
0884-0431
URN:
uuid:bd0d9755-33bc-4c1f-b3cb-46639bf79fcf
Source identifiers:
16434
Local pid:
pubs:16434

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