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Journal article

Spatiotemporal progression of localized bacterial peritonitis before and after open abdomen lavage monitored by in vivo bioluminescent imaging.

Abstract:

BACKGROUND: Bacterial peritonitis is a life-threatening abdominal infection associated with high morbidity and mortality. The rat is a popular animal model for studying peritonitis and its treatment, but longitudinal monitoring of the progression of peritonitis in live animals has been impossible until now and thus required a large number of animals. Our objective was to develop a noninvasive in vivo imaging technique to monitor the spatiotemporal spread of bacterial peritonitis. METHODS: Pe...

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Publication status:
Published

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Publisher copy:
10.1016/j.surg.2009.05.016

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
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Journal:
Surgery
Volume:
147
Issue:
1
Pages:
89-97
Publication date:
2010-01-05
DOI:
EISSN:
1532-7361
ISSN:
0039-6060
URN:
uuid:bd003de6-de1c-4252-96c5-0edd60410fac
Source identifiers:
190821
Local pid:
pubs:190821

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