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Thesis

Innate immune responses to tuberculosis vaccines

Abstract:

Tuberculosis, caused by infection with Mycobacterium tuberculosis (M.tb), remains a global health problem. Drug resistance and high rates of HIV infection have fuelled the pandemic and, although a vaccine exists, its ability to protect from pulmonary tuberculosis varies between 0 and 80%. Bacille Calmette Guerin (BCG) has been administered to billions worldwide yet its protective mechanisms remain unknown, as do the reasons for its failure to protect in many parts of the world. Modified Va...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Oxford college:
Lincoln College
Role:
Author

Contributors

Division:
MSD
Department:
RDM
Role:
Supervisor
Division:
MSD
Department:
RDM
Role:
Supervisor
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Funding agency for:
Matsumiya, M
Grant:
WTA089579/Z/09/Z
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:bcec5004-fd34-4d36-b088-c0b7e31a87f8
Local pid:
ora:9327
Deposit date:
2014-11-17

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