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Thesis

Innate immune responses to tuberculosis vaccines

Abstract:

Tuberculosis, caused by infection with Mycobacterium tuberculosis (M.tb), remains a global health problem. Drug resistance and high rates of HIV infection have fuelled the pandemic and, although a vaccine exists, its ability to protect from pulmonary tuberculosis varies between 0 and 80%. Bacille Calmette Guerin (BCG) has been administered to billions worldwide yet its protective mechanisms remain unknown, as do the reasons for its failure to protect in many parts of the world. Modified Va...

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Institution:
University of Oxford
Oxford college:
Lincoln College
Department:
Nuffield Department of Medicine
Role:
Author

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Role:
Supervisor
Role:
Supervisor
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Funding agency for:
Magali Matsumiya
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:bcec5004-fd34-4d36-b088-c0b7e31a87f8
Local pid:
ora:9327

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