Serum insulin-like growth factor II levels in normal adolescents and those with insulin dependent diabetes mellitus.
OBJECTIVE: Unlike IGF-I and its principal binding proteins, data regarding IGF-II levels have not been well defined in normal subjects and those with insulin-dependent diabetes mellitus (IDDM). We have therefore measured IGF-II, as well as IGF-I, and IGFBP-3, levels in a large cohort of subjects with IDDM and in age/sex matched controls. PATIENTS: One hundred and fourteen patients with IDDM (57 males, 57 females) and 89 control subjects (49 males, 40 females). MEASUREMENTS: Random blood sampl...Expand abstract
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